--- Query Results --- | |||||||
| Organization: | Alberta Precision Laboratories | ||||||
| Message Alert: | PLEASE NOTE: This Test Directory is in an interim state and due to changes pertaining to the DynaLIFE transition, performing site for routing has not been updated. Please refer to Laboratory Information System for appropriate routing. | ||||||
| Test Name/Synonym: | Sirolimus Level (Synonym: Rapamune, Rapamycin, SIRO) | ||||||
| Ordering Alert: | Record time of last dose on requisition or in electronic ordering system. | ||||||
| Collection Alert: | Collect within 2 hours before next dose. Best practice is to not draw from an intravenous line through which the drug has been administered as it can produce erroneous results and impact patient care. If best practice is not possible, prior consultation with the most responsible health practitioner is required. | ||||||
| LABID (Connect Care): | LAB875 | ||||||
| Specimen Type: | Blood | ||||||
| Primary Container: | LAVENDER EDTA | ||||||
| Minimum Collection Volume: | 1 mL whole blood 0.5 mL microcollection | ||||||
| Specimen Collection Requirements: | If Sirolimus, Tacrolimus, and Cyclosporine are ordered in any combination, they may be collected in one tube. | ||||||
| Test Resources: |
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| Stability and Storage: | Refrigerated – 1 week | ||||||
| Processing: | Do not centrifuge or aliquot. | ||||||
| Transportation: | Calgary: Must be received by 13:00 Monday to Friday, or 11:30 on weekends and holidays for same day analysis. Edmonton: Must be received by 13:30 Monday to Friday, or 11:00 on weekends and holidays for same day analysis. | ||||||
| Method: | Liquid Chromatography – Mass Spectrometry/Mass Spectrometry. | ||||||
| Method and Interpretation of Results: | Result to be interpreted by clinician. Interpretation is dependent upon various factors such as transplant type, time post-transplant, and concomitant immunosuppressive therapy. | ||||||
| Testing Schedule: | Daily | ||||||
| Critical Value: | Greater than 30.0 µg/L | ||||||
| Testing Area: | TDM/Toxicology | ||||||
| Performing Site: | Calgary: Diagnostic and Scientific Centre Edmonton: University of Alberta Hospital | ||||||
| Additional Test Information: | Steady state: 10-18 days | ||||||
| Contact Comments: | Calgary: Stat requests have restricted clinical indications and require review and approval by APL Medical & Scientific Staff. Contact LIC at 403-770-3600 for Pathologist On Call information. Edmonton: After hours requests require approval. Contact Client Response at 780-407-7484 for Biochemist on call information. | ||||||
| Last Updated On: | Monday, October 21, 2024 | ||||||
