--- Query Results --- | |||||||
| Organization: | Alberta Precision Laboratories | ||||||
| Message Alert: | PLEASE NOTE: This Test Directory is in an interim state and due to changes pertaining to the DynaLIFE transition, performing site for routing has not been updated. Please refer to Laboratory Information System for appropriate routing. | ||||||
| Test Name/Synonym: | Anti-Double Stranded DNA (Synonyms: Double-stranded dna antibodies, Anti-dsdna antibodies, Dsdna antibodies, Anti dna antibodies) | ||||||
| Clinical Indications: | Antibodies to dsDNA help confirm the diagnosis of Systemic Lupus Erythematosus in patients with clinical features. Following levels of anti-dsDNA antibody in SLE patients may be of use in monitoring disease activity. High antibody levels are associated with active SLE. | ||||||
| Shipping and Handling Alert: | Avoid multiple freeze thaw cycles. | ||||||
| LABID (Connect Care): | LABID 648 | ||||||
| Specimen Type: | Blood | ||||||
| Specimen Source: | Venous | ||||||
| Primary Container: | GOLD SST | ||||||
| Alternate Containers: | RAPID SERUM TUBE RED | ||||||
| Minimum Collection Volume: | 0.6 mL serum | ||||||
| Specimen Collection Requirements: | One 5 mL RAPID SERUM TUBE is acceptable within one hour of closing. | ||||||
| Test Resources: |
| ||||||
| Stability and Storage: | Calgary: Primary tube stable for 5 days in the fridge. Edmonton: Serum aliquot stable for 7 days in the fridge. Extended stability if frozen. Avoid multiple freeze thaw cycles. | ||||||
| Processing: | Edmonton: Centrifuge and aliquot serum into polypropylene or polystyrene tube and freeze. | ||||||
| Method: | Multiplex Bead Immunoassay (Bioplex) | ||||||
| Method and Interpretation of Results: | Bioplex: Negative: Less than or equal to 4 kIU/L Indeterminate: 5 - 9 kIU/L Positive: 10 or greater kIU/L | ||||||
| Routine Turn Around Time: | 2-3 days | ||||||
| Testing Schedule: | Monday to Friday | ||||||
| Reference Interval: | (Bioplex): 0 - 9 kIU/L | ||||||
| Testing Area: | Biochemistry | ||||||
| Performing Site: | Calgary: Diagnostic and Scientific Centre Edmonton: University of Alberta Hospital | ||||||
| Additional Test Information: | This test is performed by Calgary Immunochemistry and Edmonton Special Chemistry. If a patient’s Anti-dsDNA Bioplex result does not fit the clinical picture, page the on-call clinical biochemist to request add-on for dsDNA antibody by Crithidia IFA. | ||||||
| Last Updated On: | Monday, February 5, 2024 | ||||||
