Alberta Precision Laboratories

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Organization:

Alberta Precision Laboratories

Message Alert:

PLEASE NOTE: This Test Directory is in an interim state and due to changes pertaining to the DynaLIFE transition, performing site for routing has not been updated. Please refer to Laboratory Information System for appropriate routing.

Test Name/Synonym:

Y Chromosome Infertility (Synonym: Y Microdeletion, DELY, AZF)

Clinical Indications:

Fertility assessment consistent with abnormal sperm production.

Test Includes:

AZFa, AZFb, AZFc regions of the male specific region of the Y chromosome

Collection Alert:

Unopened dedicated tubes (do not share) are required for Molecular Genetics testing.

LABID (Connect Care):

LAB4134

Test Code:

CALGARY ZONE	MISCREFBL; IN MISC REF TEST NAME FIELD ENTER YCHROM MICRODEL
EDMONTON ZONE	DELY-; APPEND SPECIMEN TYPE
OTHER ZONES	NOT SPECIFIED

Specimen Type:

Blood, DNA, Other

Specimen Source:

Indicate a specimen source

Primary Container:

Lavender top EDTA

Alternate Containers:

Microcollection EDTA
DNA tube

Minimum Collection Volume:

See Specimen Collection Requirements

Specimen Collection Requirements:

For Blood Specimen (peripheral or cord blood)
EDTA tubes should be completely full, 2/3 full at minimum, testing may be affected by partial draw

For Patients over 20 kg: 2 EDTA tubes each containing 3.0 mL of blood
For Patients up to 20 kg: 2 EDTA tubes each containing 2.0 mL of blood

For Extracted DNA

Submit 10ug @ >100ng/uL.

Test Resources:

Pre-test Counselling Information-Genetic and Genomic Testing

Submit requests using requisition or Connect Care online order entry:

Molecular Genetics Requisition

Please ensure all required information, including patient's clinical history/indication, is provided on the requisition.

Stability and Storage:

Room temperature: For all specimen types (except frozen tissue) if being shipped on same day of collection (preferred).
Refrigerated: If shipping is delayed.

Processing:

Do not centrifuge or aliquot specimens.

Transportation:

Transport all specimen types at room temperature.
Specimens must not freeze in transit.

Specimens, should be received by the Molecular Genetics Laboratory:

Within 5 days of date of collection for Blood and Extracted DNA specimens.
And must include the original paper requisition and accompanying documentation

Transport specimens (except extracted DNA) to Molecular Genetics Laboratory via UAH Specimen Control WMC 4B2.10.
For Extracted DNA samples only, transport specimens to Molecular Genetics Laboratory via UAH Shipping Receiving, UNIVERSITY OF ALBERTA HOSPITAL, 8440 112 STREET, Room: 8-26 MSB, EDMONTON, T6G 2B7

Blood and Extracted DNA specimens

Are received Mon – Fri: 07:30 to 15:00.
If received after 15:00, will be processed on the next working day.

Method:

Microsatellites.

Routine Turn Around Time:

Routine: 6 to 8 weeks, Stat: 1 to 2 weeks

Reference Interval:

Interpretation provided on report.

Testing Area:

Molecular Genetics

Performing Site:

University of Alberta Hospital

Contact Comments:

For additional information refer to Genetics and Genomics webpage or contact:
Molecular Genetics North: 780-407-1434 (phone), 780-407-1761 (fax)

Last Updated On:

Monday, October 26, 2020

Date of Last Review:

Aug 1 2022 12:00AM