--- Query Results --- | |||
| Organization: | Alberta Precision Laboratories | ||
| Test Name/Synonym: | Cold Agglutinin Titre (Cold Agglutinin Screen, Cold Agglutinin Titration, 4 degrees) | ||
| Clinical Indications: | Detection of cold reactive antibodies associated with Autoimmune Hemolytic Anemia and Cold Agglutinin Disease. Cold agglutinins can occur in a variety of acute infections including EBV, CMV, Mycoplasma Pneumoniae and some lymphoproliferative disorders. Cold agglutinins are usually IgM autoantibodies directed against the Ii antigens of human RBCs. No longer indicated for atypical pneumonia. See Mycoplasma Infections – Respiratory | ||
| Test Includes: | Cold Agglutinin Screen and/or Cold Agglutinin Titre | ||
| LABID (Connect Care): | LAB849 | ||
| Specimen Type: | Whole Blood | ||
| Specimen Source: | Venous | ||
| Primary Container: | Lavender - EDTA | ||
| Minimum Collection Volume: | 2 mL | ||
| Stability and Storage: | Refrigerated for 7 days after testing. | ||
| Transportation: | Specimens transported should be transported at room temperature and arrive the same day as collection. | ||
| Method and Interpretation of Results: | Cold agglutinins may be present in healthy individuals. A titre of 40 or greater may indicate the presence of clinically significant cold reactive autoantibody. | ||
| Testing Schedule: | Daily | ||
| Testing Area: | Transfusion Medicine | ||
| Performing Site: | Foothills Medical Centre University of Alberta Hospital | ||
| Last Updated On: | Wednesday, January 29, 2025 | ||
