Alberta Precision Laboratories

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Organization:

Alberta Precision Laboratories

Message Alert:

PLEASE NOTE: This Test Directory is in an interim state and due to changes pertaining to the DynaLIFE transition, performing site for routing has not been updated. Please refer to Laboratory Information System for appropriate routing.

Test Name/Synonym:

Vancomycin Level, Pre-Dose

Ordering Alert:

Record time of last dose on requisition or in electronic ordering system.
For all other Vancomycin orders refer to Vancomycin Level, Other.

Collection Alert:

Collect within 30 minutes before next dose when at steady state.

For adults: steady state is reached approximately 30 hours if normal renal function, before 4th dose if q12h dosing or before 5th dose if q8h dosing.

For pediatrics: steady state is reached approximately 24 hours if normal renal function and after at least 2 maintenance doses.

Best practice is to not draw from an intravenous line through which the drug has been administered as it can produce erroneous results and impact patient care. If best practice is not possible, prior consultation with the most responsible health practitioner is required.

LABID (Connect Care):

LAB39

Specimen Type:

Blood

Primary Container:

MINT LIHEP PST

Minimum Collection Volume:

Calgary Zone: 0.2 mL plasma
Central, Edmonton, North, South Zones: 0.5 mL plasma

Specimen Collection Requirements:

Serum is not an acceptable specimen due to interference with rheumatoid factor.

Test Resources:

General Laboratory Requisition – 21302

Half-life and Time to Steady State

Calgary Zone: Microcollection Minimum Whole Blood Volumes

Calgary Zone: Critical Values

Processing:

North Zone: GPRH: Centrifuge and aliquot plasma within two hours of collection.

Testing Schedule:

Daily

Reference Interval:

10 - 20 mg/L

Critical Value:

Greater than 25.0 mg/L

Testing Area:

Biochemistry

Performing Site:

Calgary Zone	Alberta Children's Hospital Foothills Medical Centre Peter Lougheed Centre Rockyview General Hospital South Health Campus
Central Zone	Red Deer Regional Hospital Centre
Edmonton Zone	Grey Nuns Hospital Misericordia Hospital Royal Alexandra Hospital Sturgeon Community Hospital University of Alberta Hospital
North Zone	Northern Lights Regional Health Centre, Fort McMurray Grande Prairie Regional Hospital
South Zone	Chinook Regional Hospital, Lethbridge Medicine Hat Regional Hospital

Additional Test Information:

Steady state: 1-2 days

Peak or post-dose levels are not recommended.

Vancomycin Levels greater than 15 mg/L increase risk of nephrotoxicity.

Routine monitoring of vancomycin levels is not generally recommended.

All performing sites except University of Alberta Hospital:
Vancomycin levels may be undetectable or falsely low in patients with elevated Immunoglobulins. Contact Laboratory Senior Staff to arrange for alternate testing if required.

For more information refer to Bugs and Drugs

Contact Comments:

1-877-868-6848

Last Updated On:

Tuesday, June 11, 2024