Alberta Precision Laboratories

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Organization:

Alberta Precision Laboratories

Test Name/Synonym:

Cortisol, Saliva (Synonym: Corticosteroid, Saliva; Salivary Cortisol; Sacor)

Clinical Indications:

This test is useful in the screening and monitoring of treatment in Cushing’s disease or syndrome.

Ordering Alert:

Calgary: This test is available for Endocrinologists only

Collection Alert:

Preferred collection time	23:00 to 00:00
Acceptable collection time	07:00 to 09:00

Special collection container must be obtained. Patients should refer to the Saliva Cortisol patient instruction sheets for information on how to obtain a test kit.

Laboratory Staff:

Calgary:
Email APL.CGYToxicologyMLA@albertaprecisonlabs.ca to request test kits.

Edmonton:
Email edm.uahreagentroom@aplabs.ca – (Monday through Friday) to request test kits.

Note: An estimated 3 – 5 business days is required to prepare and ship orders to collection site.

Shipping and Handling Alert:

Keep refrigerated. The specimen should be received at the testing lab as soon as possible.

LABID (Connect Care):

LAB4698

Specimen Type:

Saliva

Primary Container:

Salivette®

Minimum Collection Volume:

0.5 mL saliva

Specimen Collection Requirements:

Saliva in Salivette® collection container

Saliva in Salivette® collection container.
Refer to patient instructions in Test Resources section below for collection information.

Test Resources:

General Laboratory Requisition – 21302 - write test name under "Additional Tests"

Patient instructions: Saliva Cortisol

Method:

LC-MS/MS (liquid chromatography-mass spectrometry/mass spectrometry)

Testing Schedule:

Test is performed within two weeks of receipt

Reference Interval:

Collection Time	nmol/L
07:00 to 09:00	2.8 to 21.0
23:00 to 00:00	Less than 2.8

Testing Area:

Calgary: TDM/Toxicology
Edmonton: Biochemistry

Performing Site:

Calgary: Diagnostic and Scientific Centre
Edmonton: University of Alberta Hospital

Additional Test Information:

This test is performed by Calgary Analytical Toxicology and Edmonton Special Chemistry.

Last Updated On:

Thursday, April 24, 2025

Registered Trademark Comments:

Salivette® is a registered trademark of SARSTEDT AG & Co. KG