Alberta Precision Laboratories

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Organization:

Alberta Precision Laboratories

Message Alert:

PLEASE NOTE: This Test Directory is in an interim state and due to changes pertaining to the DynaLIFE transition, performing site for routing has not been updated. Please refer to Laboratory Information System for appropriate routing.

Test Name/Synonym:

Gentamicin Level, Pre-dose (Synonym: Trough Gentamicin Level)

Ordering Alert:

Record time of last dose on requisition or in electronic ordering system

Collection Alert:

Conventional dosing: Collect within 60 minutes before dose, when at steady state (usually after 3-4 doses in patients with normal renal function)
High dose extended interval dosing: Collect within 60 minutes before dose. For first level, collect before second dose.

Best practice is to not draw from an intravenous line through which the drug has been administered as it can produce erroneous results and impact patient care. If best practice is not possible, prior consultation with the most responsible health practitioner is required.

LABID (Connect Care):

LAB26

Specimen Type:

Blood

Primary Container:

MINT LIHEP PST

Alternate Containers:

GOLD SST

Minimum Collection Volume:

Calgary Zone: 0.2 mL plasma or serum
Central, Edmonton, North, South Zones: 0.5 mL plasma or serum

Test Resources:

General Laboratory Requisition – 21302

Half-life and Time to Steady State

Calgary Zone: Microcollection Minimum Whole Blood Volumes

Calgary Zone: Critical Values

Method and Interpretation of Results:

If patient is receiving extended interval dosing the target trough is less than 0.5 mg/L. Dosing is 4 to 10 mg/kg and interval is 24 hours or more.

Reference Interval:

Less than 2.0 mg/L

Critical Value:

Greater than 1.9 mg/L

Testing Area:

Biochemistry

Performing Site:

Calgary Zone	Alberta Children's Hospital Foothills Medical Centre Peter Lougheed Centre Rockyview General Hospital
Central Zone	Red Deer Regional Hospital Centre
Edmonton Zone	Royal Alexandra Hospital University of Alberta Hospital
North Zone	Grande Prairie Regional Hospital or referred out to University of Alberta Hospital
South Zone	Chinook Regional Hospital, Lethbridge Medicine Hat Regional Hospital

Additional Test Information:

Steady State: approximately 1 day

North Zone: GPRH: intramuscular injection (IM): pre-dose (trough) level is suggested.

For more information refer to www.bugsanddrugs.org

Last Updated On:

Thursday, January 11, 2024