--- Query Results --- | |||
| Organization: | Alberta Precision Laboratories | ||
| Message Alert: | PLEASE NOTE: This Test Directory is in an interim state and due to changes pertaining to the DynaLIFE transition, performing site for routing has not been updated. Please refer to Laboratory Information System for appropriate routing. | ||
| Test Name/Synonym: | Tyrosinemia Monitoring, Dried Blood Spot | ||
| Clinical Indications: | For therapeutic monitoring of patients with a known diagnosis of Tyrosinemia or Alkaptonuria. | ||
| Ordering Alert: | Test suitable for monitoring known patients and not for diagnostic testing. Monitoring that requires accurate quantification of any of these amino acids individually should be done using the Amino Acids Quantitation, Plasma test. | ||
| Shipping and Handling Alert: | Ensure the blood spot is dry before closing the protective flap. | ||
| LABID (Connect Care): | LAB7002 | ||
| Test Code: | 14342 | ||
| Specimen Type: | Dried Blood Spot | ||
| Primary Container: | Newborn Metabolic Screening Blood Spot Requisition (card) | ||
| Specimen Collection Requirements: | Ensure that expiry date of Newborn Metabolic Screening Blood Spot Requisition (card) has not been exceeded before proceeding with collection. Use a heel poke if patient is less than one year old or a finger poke if older. Collect two saturated blood spots on the Newborn Metabolic Screening card. Alternative:
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| Test Resources: | Submit requests using the Newborn Metabolic Screening Blood Spot Requisition (card). Please ensure all required information is provided, and "Tyrosinemia" is written on the requisition (card). | ||
| Stability and Storage: | Room Temperature | ||
| Processing: | Dry the Newborn Metabolic Screening card for a minimum of 3 hours with protective card flap folded back. Please follow collection instructions on the back of the blood spot card. Write "FOR TYROSINEMIA ONLY" on the newborn metabolic screening card. | ||
| Transportation: | Transport at rooom temperature | ||
| Method: | Flow-injection tandem mass spectrometry (FI-MS/MS) | ||
| Method and Interpretation of Results: | Amino acids and succinylacetone concentrations are measured using flow-injection electrospray-ionization tandem mass spectrometry (FI-MS/MS) with stable-isotope labelled internal standards. | ||
| Routine Turn Around Time: | 4 days | ||
| Testing Schedule: | Daily | ||
| Reference Interval: | Reference intervals are age-dependent and will be provided on the report. | ||
| Testing Area: | Newborn Metabolic Screening & Biochemical Genetics | ||
| Contact Comments: | Newborn Metabolic Screening & Biochemical Genetics North 780-407-8820 | ||
| Last Updated On: | Friday, February 10, 2023 | ||
