Alberta Precision Laboratories

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Organization:

Alberta Precision Laboratories

Message Alert:

PLEASE NOTE: This Test Directory is in an interim state and due to changes pertaining to the DynaLIFE transition, performing site for routing has not been updated. Please refer to Laboratory Information System for appropriate routing.

Test Name/Synonym:

Fibrosis-4 (ALT, AST, PLT) (Synonym: FIB4, FIB-4, FATTY LIVER)

Clinical Indications:

This test includes calculation of FIB-4 score based on age and a combination of lab tests (aspartate aminotransferase [AST], alanine aminotransferase [ALT], and platelet count). FIB-4 is a well-validated index used to risk stratify patients with non-alcoholic fatty liver disease (NAFLD) into high, intermediate, and low risk of developing cirrhosis over the next 10 years.

Test Includes:

This order provides the following lab results:

FIB - 4 score.
Alanine Aminotransferase (ALT)
Aspartate Aminotransferase (AST)
Platelet count

Ordering Alert:

Do not order FIB-4 together with the individual ALT, AST, or platelet count order.

LABID (Connect Care):

LAB5191

Specimen Type:

Blood

Primary Container:

MINT LIHEP PST and LAVENDER EDTA

Alternate Containers:

GOLD SST and LAVENDER EDTA

Minimum Collection Volume:

0.2 mL plasma or serum
1 mL whole blood (Microcollection minimum 0.5 mL whole blood)

Test Resources:

General Laboratory Requisition – 21302 – write test name under “Additional Tests”

Calgary Zone: Microcollection Minimum Whole Blood Volumes

Testing Schedule:

Daily

Reference Interval:

No reference intervals

Testing Area:

Biochemistry

Performing Site:

Calgary Zone	Alberta Children's Hospital Diagnostic and Scientific Centre Didsbury District HC Foothills Medical Centre High River General Hospital Peter Lougheed Centre Rockyview General Hospital South Health Campus Strathmore District Health Services
Central Zone	Camrose, St. Mary’s Hospital Red Deer Regional Hospital Centre Wainwright HC
Edmonton Zone	Cross Cancer Institute Edmonton Base Lab Grey Nuns Hospital Misericordia Hospital Royal Alex Hospital Sturgeon Hospital University of Alberta Hospital
North Zone	Athabasca HC Barrhead HC Beaverlodge Municipal Hospital Bonnyville HC Central Peace HC Edson HC Fairview HC Grande Cache HC Grande Prairie Regional Hospital High Prairie HC Hinton HC Lac La Biche HC Manning HC Northern Lights Regional HC (FMH) Peace River HC Slave Lake HC Valleyview HC Westlock HC Whitecourt HC Or referred to Edmonton Base Lab
South Zone	Chinook Regional Hospital Medicine Hat Regional Hospital

Additional Test Information:

FIB-4 score is a key step in several provincial clinical pathways:

Last Updated On:

Thursday, February 1, 2024