--- Query Results --- | |||||||
| Organization: | Alberta Precision Laboratories | ||||||
| Message Alert: | PLEASE NOTE: This Test Directory is in an interim state and due to changes pertaining to the DynaLIFE transition, performing site for routing has not been updated. Please refer to Laboratory Information System for appropriate routing. | ||||||
| Test Name/Synonym: | Anti-Beta-2 Glycoprotein (Synonyms: AB2G, B2GAB, Beta-2 Glycoprotein, Antiphospholipid antibodies, APA) | ||||||
| Clinical Indications: | Presence of antiphospholipid antibodies including anti-beta-2 glycoprotein aid in the diagnosis of systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS) in association with other lab tests and specific clinical manifestations. | ||||||
| Test Includes: | Anti-Beta-2-Glycoprotein Antibody IgG Isotype For query APS, order ANTIPHOSPHOLIPID SYNDROME INVESTIGATION. | ||||||
| LABID (Connect Care): | LAB4602 | ||||||
| Specimen Type: | Blood | ||||||
| Specimen Source: | Blood | ||||||
| Primary Container: | GOLD SST | ||||||
| Alternate Containers: | RED Microcollection: GOLD SST | ||||||
| Minimum Collection Volume: | 1.0 mL serum | ||||||
| Test Resources: |
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| Stability and Storage: | Calgary: Primary tube stable for 5 days in the fridge. Edmonton: Serum aliquot stable for 7 days in the fridge. Extended stability if frozen. Avoid multiple freeze thaw cycles. | ||||||
| Processing: | For testing sent to Calgary: Centrifuge. Do not aliquot. For testing sent to Edmonton: Centrifuge and aliquot serum into polypropylene or polystyrene tube and freeze. | ||||||
| Transportation: | For testing sent to Calgary: Transport at refrigerated temperatures. For testing sent to Edmonton: Transport frozen. (dry ice if available) | ||||||
| Method: | Multiplex bead immunoassay (Bioplex) | ||||||
| Method and Interpretation of Results: | Presence of antiphospholipid antibodies including anti-beta-2 glycoprotein are one of the lab criteria that aid in the diagnosis of systemic lupus erythematosus in association with ANA, C3, C4. anti-dsDNA, anti-Smith, and specific clinical manifestations. Moderate to strong positive results for anti-cardiolipin IgG and/or anti-beta-2 glycoprotein 1 IgG antibodies in association with specific clinical manifestations may be diagnostic for APS. | ||||||
| Routine Turn Around Time: | 1 – 3 days | ||||||
| Testing Schedule: | Monday to Friday | ||||||
| Reference Interval: | Negative: Less than 20.0 U/mL Low Positive: 20.0 - 40.0 U/mL Moderate Positive: 40.1 - 80.0 U/mL High Positive: Greater than 80.0 U/mL | ||||||
| Testing Area: | Biochemistry | ||||||
| Performing Site: | Calgary Zone: Diagnostic and Scientific Centre Edmonton Zone: University of Alberta Hospital | ||||||
| Additional Test Information: | For STAT testing, contact the Clinical Biochemist on call. | ||||||
| Last Updated On: | Monday, April 29, 2024 | ||||||
