--- Query Results --- | |||
PLEASE NOTE: This Test Directory is in an interim state and due to changes pertaining to the DynaLIFE transition, performing site for routing has not been updated. Please refer to Laboratory Information System for appropriate routing. | |||
| Organization: | Alberta Precision Laboratories | ||
| Test Name/Synonym: | Celiac Disease Screen - Calgary Zone (CLS) | ||
| Test Code: | CELIAC OR TTG | ||
| Primary Container: | SST (GOLD) | ||
| Specimen Collection Requirements: | One 3.5 mL gold top SST tube PSC only: One 5 mL orange top RST tube is acceptable within one hour of lab closing. Microcollection Minimum Whole Blood Volumes. | ||
| Testing Schedule: | Test performed Monday to Friday | ||
| Reference Interval: | Anti-Endomysial Antibodies - negative Tissue Transglutaminase Antibody IgA and IgG - < 15.0 kIU/L | ||
| Testing Area: | Immunochemistry | ||
| Performing Site: | Diagnostic and Scientific Centre | ||
| Additional Test Information: | Test screen for gluten intolerance (Celiac Disease) Initial test of Celiac Disease Screen includes TTG IgA. The current method has the ability to determine whether a sample has low IgA levels. Additional reflexive assays will be ordered as required and may include Anti-Endomysial Antibodies and TTG IgG. Physician Information: Initiating a gluten-free diet prior to referral or prior to screening will interfere with the diagnostic tests for celiac disease. Please note that individuals may exhibit a wide range of responses to gluten challenge over varying periods of time. Some patients only require a diet containing gluten (minimum of 3 g/day gluten or approximately 1-2 slices of bread/day) for at least 2 weeks to exhibit histological changes and at least 4 weeks for tTG IgA levels to increase. Others may require a challenge for as long as two years prior to the development of intestinal injury or antibody response. Celiac disease serology during the challenge should be repeated every 4-6 months or immediately with the development of symptoms. Click here to view a diagnostic algorithm. | ||
| Last Updated On: | Friday, October 14, 2022 | ||
