Alberta Precision Laboratories

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Organization:

Alberta Precision Laboratories

Message Alert:

PLEASE NOTE: This Test Directory is in an interim state and due to changes pertaining to the DynaLIFE transition, performing site for routing has not been updated. Please refer to Laboratory Information System for appropriate routing.

Test Name/Synonym:

Anti-Xa Rivaroxaban Level
(Synonym: anti Xa Rivaroxaban, Xarelto)

Clinical Indications:

Quantitation of Rivaroxaban concentration (ng/mL) as measured using a specific Anti-Xa based assay.

Ordering Alert:

This assay is calibrated for Rivaroxaban, it cannot be used to quantitate other medications but it does give a qualitative indication of whether any such medications are present. If the Anti Xa is not for the purpose of monitoring Rivaroxaban order other specific Anti Xa assays (Unfractionated Heparin, LMWH, or Apixaban). For anticoagulants not mentioned default order to Anti Xa Unfractionated heparin.

For sites referring to Edmonton, Anti-Xa Heparin Level will also be performed.

Central, Edmonton and North Zones:
Note: for urgent qualitative assessment of any FXa inhibitor (eg. rivaroxaban, apixaban, edoxaban, fondaparinux, etc.) order an “Anti-Xa Heparin Level”. The Anti-Xa Heparin Level is calibrated to Heparin units, so cannot be used to quantitate other medications but does give a qualitative indication of whether any such medications are present.

Collection Alert:

Test cannot be collected by Mobile Collection Service

Shipping and Handling Alert:

Specimens are time sensitive.

LABID (Connect Care):

LAB4361A

Test Code:

CALGARY ZONE

XA RIV

Specimen Type:

Blood

Specimen Source:

Arterial, Venous, Central Line

Primary Container:

LT BLUE CITRATE

Minimum Collection Volume:

Adults: One 2.7 mL LT blue citrate tube, allow the vacuum tube to completely fill, minimum fill is to frosted line on tube.
Pediatric and Neonate: One 2.7 mL or 1.8 mL LT blue citrate tube, allow the vacuum tube to completely fill, minimum fill is to frosted line on tube.

Specimen Collection Requirements:

It is important to fill tube to maximum draw.
Mix well immediately after collection by inverting tube 3 to 4 times.
Must be collected by venipuncture. If venous access not available, sample can be drawn from a line but 6x the volume of the line or 5 mL (whichever is less) must be removed prior to collection.
When using a winged blood collection set (butterfly needle), a discard tube must be used to remove the air in the tubing, if only a citrate tube is drawn or is the first tube drawn.

Test Resources:

General Laboratory Requisition – 21302

Stability and Storage:

Room temperature – 3.5 hours

Processing:

For specimens that will be received beyond stability:

Centrifuge to obtain platelet poor plasma (platelet count <10 x 10*9/L)
Aliquot plasma into plastic aliquot tube and freeze.

Transportation:

Room temperature – uncentrifuged
Frozen (dry ice if available)

Routine Turn Around Time:

Stat testing is available

Testing Schedule:

Daily

Reference Interval:

See Laboratory Report.

Critical Value:

See Laboratory Report.

Testing Area:

Hematology

Performing Site:

Calgary: Foothills Medical Centre

Last Updated On:

Thursday, June 23, 2022