--- Query Results --- | |||
| Organization: | Alberta Precision Laboratories | ||
| Message Alert: | PLEASE NOTE: This Test Directory is in an interim state and due to changes pertaining to the DynaLIFE transition, performing site for routing has not been updated. Please refer to Laboratory Information System for appropriate routing. | ||
| Test Name/Synonym: | Adenine Phosphoribosyltransferase (Referred Test) (Synonym: APRT, 2,8-DIHYDROXYADENINE) | ||
| Clinical Indications: | This test is for the further investigation of a patient with a high clinical suspicion and/or initial laboratory results consistent with adenine phosphoribosyltransferase deficiency. | ||
| Ordering Alert: | This test is considered specialty testing; this test will be cancelled if sufficient clinical justification is not provided.
This test should NOT be used as a primary screen for adenine phosphoribosyltransferase deficiency. Clinical findings of urolithiasis or crystalline nephropathy WITH evidence of elevated urine 2,8-dihydroxyadenine (2,8 DHA or DHA; using Purines and Pyrimidines) are required for testing to proceed. | ||
| Collection Alert: | Newborn Metabolic Screen Blood Spot Requisition (card) is required for testing. Clearly indicate “APRT” on the blood spot card. | ||
| Shipping and Handling Alert: | Allow blood spots to dry minimum 3 hours at room temperature before packaging for shipment. Store and ship at room temperature. If collecting whole blood, specimen must be stored and shipped at 4°C, and MUST be received by the Alberta Children’s Hospital Biochemical Genetics Laboratory (ACH) or University of Alberta Hospital Laboratory (UAH) within 24 hours of time of collection. ACH or UAH lab will spot the blood once specimen is received. | ||
| LABID (Connect Care): | LAB4003 | ||
| Primary Container: | Newborn Metabolic Screening Blood Spot Requisition (card) | ||
| Alternate Containers: | Lavender top EDTA | ||
| Minimum Collection Volume: | 3 blood spots | ||
| Specimen Collection Requirements: | This test is referred out to the University of San Diego Biochemical Genetics Laboratory; see APRT (Adenine Phosphoribosyltransferase) in the UCSD Clinical Test and Assays. | ||
| Test Resources: | Submit request using the applicable requisition or Connect Care online order entry:
Please ensure all required information, including patient's clinical history/indication, is provided on the requisition. | ||
| Testing Area: | Referred Out Specimens should be sent to UAH External Send Out bench (North) or ACH Genetics & Genomics (South). | ||
| Performing Site: | Referred out to University of San Diego (UCSD) Biochemical Genetics Laboratory | ||
| Last Updated On: | Monday, November 27, 2023 | ||
| Date of Last Review: | Aug 1 2022 12:00AM | ||
