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| Organization: | Alberta Precision Laboratories | ||||
| Message Alert: | PLEASE NOTE: This Test Directory is in an interim state and due to changes pertaining to the DynaLIFE transition, performing site for routing has not been updated. Please refer to Laboratory Information System for appropriate routing. | ||||
| Test Name/Synonym: | Invariant NKT Cells (Synonym: iNKT, Invariant NK Cells) | ||||
| Clinical Indications: | iNKT deficiency can be seen in XLP1 (SH2D1A gene mutation), Omenn syndrome, CVID and Hyper IgE syndrome.
Peripheral blood iNKT cell enumeration is performed by Flow Cytometry based on co-expression of CD3, TCRvα24 and TCRvß11. | ||||
| Test Includes: | The percentage and absolute iNKT counts are reported. | ||||
| Collection Alert: | Collect a normal, preferably age-matched, peripheral blood specimen and transport with patient specimen. | ||||
| LABID (Connect Care): | LAB4468 | ||||
| Specimen Type: | Blood | ||||
| Primary Container: | GREEN NA HEP | ||||
| Alternate Containers: | LAVENDER EDTA | ||||
| Minimum Collection Volume: | Pediatrics: 5 mL Adults: 10 mL | ||||
| Test Resources: |
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| Stability and Storage: | Stable for 48 hours. | ||||
| Processing: | DO NOT centrifuge or freeze. | ||||
| Transportation: | Within Calgary Zone: transport at room temperature. For testing sent to Calgary from outside Calgary Zone:
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| Testing Schedule: | Monday to Friday | ||||
| Reference Interval: | See laboratory report | ||||
| Testing Area: | Flow Cytometry | ||||
| Performing Site: | Calgary: Foothills Medical Centre | ||||
| Additional Test Information: | Requisition must accompany the specimen. Patient history must be included on the requisition. | ||||
| Contact Comments: | 1-877-868-6848 | ||||
| Last Updated On: | Monday, January 8, 2024 | ||||
