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| Organization: | Alberta Precision Laboratories | ||||||||
| Message Alert: | PLEASE NOTE: This Test Directory is in an interim state and due to changes pertaining to the DynaLIFE transition, performing site for routing has not been updated. Please refer to Laboratory Information System for appropriate routing. | ||||||||
| Test Name/Synonym: | IL-12 Pathway (Synonym: CD212, IL12RB1, Mendelian Susceptibility To Mycobacterial Disease, PSTAT4) | ||||||||
| Clinical Indications: | IL12Rβ1 (CD212) deficiency/pSTAT4 downregulation results in defective production of IFN-γ and susceptibility to intracellular pathogens including mycobacterial, salmonella and viral infections. | ||||||||
| Test Includes: | Expression of IL-12Rbeta1 (CD212) and pSTAT4 on activated lymphocytes are reported. pSTAT4 is temporarily unavailable. | ||||||||
| Collection Alert: | Collect a normal, preferably age-matched, peripheral blood specimen and transport with patient specimen. | ||||||||
| Test Code: |
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| Primary Container: | GREEN NA HEP | ||||||||
| Minimum Collection Volume: | 4 mL | ||||||||
| Specimen Collection Requirements: | Adult: Collect two GREEN NA HEP tubes Pediatric: Collect one GREEN NA HEP tube | ||||||||
| Test Resources: |
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| Stability and Storage: | 48 hours
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| Processing: | DO NOT centrifuge, refrigerate or freeze.
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| Transportation: | Within Calgary Zone: transport at room temperature. For testing sent to Calgary from outside Calgary Zone:
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| Testing Schedule: | Monday to Friday | ||||||||
| Reference Interval: | See laboratory report | ||||||||
| Performing Site: | Calgary: Foothills Medical Centre | ||||||||
| Additional Test Information: | Requisition must accompany the specimen. Patient history must be included on the requisition | ||||||||
| Contact Comments: | 1-877-868-6848 | ||||||||
| Last Updated On: | Tuesday, May 11, 2021 | ||||||||
