Alberta Precision Laboratories

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Organization:

Alberta Precision Laboratories

Message Alert:

PLEASE NOTE: This Test Directory is in an interim state and due to changes pertaining to the DynaLIFE transition, performing site for routing has not been updated. Please refer to Laboratory Information System for appropriate routing.

Test Name/Synonym:

Cortisol, Saliva (Synonym: Corticosteroid, Saliva; Salivary Cortisol; Sacor)

Clinical Indications:

This test is useful in the screening and monitoring of treatment in Cushing’s disease or syndrome.

Ordering Alert:

Calgary: This test is available for Endocrinologists only

Collection Alert:

Preferred collection time	23:00 to 00:00
Acceptable collection time	07:00 to 09:00

Special collection container must be obtained.

Shipping and Handling Alert:

Keep refrigerated. The specimen should be received at the testing lab as soon as possible.

LABID (Connect Care):

LAB4698

Test Code:

CALGARY ZONE	SACOR
CENTRAL ZONE	MISC
EDMONTON ZONE	SACOR
NORTH ZONE	LAB4698
SOUTH ZONE	CORSAL

Specimen Type:

Saliva

Primary Container:

Salivette®

Minimum Collection Volume:

0.5 mL saliva

Specimen Collection Requirements:

Saliva in Salivette® collection container

Instructions for collecting saliva with the Salivette®:

Collect saliva sample between 11:00 p.m. and midnight while resting. Do not eat anything or drink any fluids 1 hour before collecting saliva. Do not brush teeth before collecting saliva.
Remove lid from tube and set aside.
Tip swab directly into mouth. Do not touch the swab with your fingers.
Chew gently until fully saturated with saliva (usually 3-5 minutes).
Replace swab into the tube without touching with fingers and cap firmly with lid.
Keep refrigerated until tube is returned to the lab.

Test Resources:

General Laboratory Requisition – 21302 - write test name under "Additional Tests"

Patient instructions: Saliva Cortisol

Calgary: Collection containers are available only through offices of the ordering Endocrinologist or the Calgary Analytical Toxicology Department at 403-770-3620.
Edmonton: Collection containers are available at University of Alberta Hospital, Royal Alexandra Hospital, Grey Nuns Hospital, and Misericordia Hospital outpatient laboratories.

Method:

LC-MS/MS (liquid chromatography-mass spectrometry/mass spectrometry)

Testing Schedule:

Test is performed within two weeks of receipt

Reference Interval:

Collection Time	nmol/L
07:00 to 09:00	2.8 to 21.0
23:00 to 00:00	Less than 2.8

Testing Area:

Calgary: TDM/Toxicology
Edmonton: Biochemistry

Performing Site:

Calgary: Diagnostic and Scientific Centre
Edmonton: University of Alberta Hospital

Additional Test Information:

This test is performed by Calgary Analytical Toxicology and Edmonton Special Chemistry.

Last Updated On:

Monday, June 7, 2021

Registered Trademark Comments:

Salivette® is a registered trademark of SARSTEDT AG & Co. KG