Alberta Precision Laboratories

--- Query Results ---

Organization:

Alberta Precision Laboratories

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Test Name/Synonym:

Metanephrines, Urine - Edmonton Zone

Clinical Indications:

Urine Metanephrines should be the initial test requested in adults where pheochromocytoma is suspected.

Primary Container:

24 hour urine, acid bottle (25 mL, 6 mol/L HCl) (NOT to be used for spot collections)

Specimen Collection Requirements:

See 24 Hour Urine Collection - Patient Instructions
Spot urine accepted on children; must be acidified to pH <3 or frozen within 4 hours of collection by the lab receiving the specimen.
pH must be adjusted to < 3 (pH paper) within 4 hours of collection by drop wise addition of 6N HCl.

For three days before and during collection avoid drug products containing acetaminophen, ASA/salicylate, buspirone, cimetidine, codeine, isoproterenol, labetalol, L-dopa, mandelamine, MAO inhibitors (e.g. phenelzine, tranylcypromine), metoclopramide, methyldopa, and oxycodone. Patient's physician must be consulted about medication discontinuation.

During collection avoid bananas, caffeinated beverages, chocolate, vanilla, and peppers.

Processing:

Require 10 mL aliquot.
Test requires creatinine result for interpretation.
Please send additional 2 mL aliquot for creatinine testing.
Referred specimens - send refrigerated if received at UAH lab within 40 hours of collection, otherwise freeze.
If spot specimen and not acidified, freeze within 4 hours of collection and send frozen.

Testing Schedule:

Test performed within 2 weeks of receipt of sample.

Reference Interval:

Metanephrines, Urine, 24 Hr

Metanephrine, Urine 24 Hr (µmol/d) Normal Reference Ranges

Age (years)

Male

Female

U/X

< 3

Not Available

3 up to 10

<0.5

<0.7

10 up to 13

<1.0

<0.6

<1.0

13 up to 18

<1.1

<0.9

<1.1

18 up to 30

<1.3

<0.9

<1.3

30 up to 40

<1.3

<0.9

<1.3

40 up to 50

<1.3

<0.9

<1.3

50 up to 60

<1.3

<0.9

<1.3

60 up to 70

<1.3

<0.9

<1.3

>70

<1.3

<0.9

<1.3

Normetanephrine, Urine 24 Hr (µmol/d) Normal Reference Ranges
Age (years)	Male	Female	U/X
< 3	Not Available
3 up to 10	<0.9	<0.8	<0.9
10 up to 13	<2.3	<1.5	<2.3
13 up to 18	<2.5	<1.6	<2.5
18 up to 30	<3.3
30 up to 40	< 2.7
40 up to 50	< 3.0
50 up to 60	< 4.3
60 up to 70	< 4.2
>70	< 3.3

Metanephrines, Urine, Random

Metanephrine/Creatinine Ratio (µmol/mmol) Normal Reference Ranges
Age (years)	Male	Female	U/X
< 3	<0.24
3 up to 10	<0.19
10 up to 13	<0.12
13 up to 18	<0.09
> 18	Not Accepted

Normetanephrine/Creatinine Ratio (µmol/mmol) Normal Reference Ranges
Age (years)	Male	Female	U/X
< 3	<0.58
3 up to 10	<0.44
10 up to 13	<0.26
13 up to 18	<0.18
> 18	Not Accepted

Testing Area:

Toxicology

Performing Site:

University of Alberta Hospital

Last Updated On:

Monday, March 21, 2022

Date of Last Review:

Jun 1 2016 12:00AM