--- Query Results ---

  
Program:Genetics and Genomics
 
Test Name:Cystinuria / Homocystinuria Screen (G&G South ACH)
Test Code:NP-U
Performing Site: Alberta Children's Hospital
Performing Dept:Biochemical Genetics
 
Availability:Test performed on a weekly basis.
TAT:8 days
 
Preferred Tube/Container:Random specimen: plain urine container
 
Specimen Requirements:Collect a 5 to 10 mL random urine sample.
 
Min. Sample Required:1.0 mL urine.
 
Specimen Processing:1.  If specimen is transferred to secondary aliquot tube or container, write "urine" on label.
2.  Freeze.
 
Specimen Handling:Transport frozen samples on ice. Samples must not thaw during transport.
 
Additional Information:Samples will be rejected if:
  • Primary container or aliquot tube received thawed
  • Sample type not written on aliquot tube label
  •  
    Requisition/Form:Submit request using Biochemical Genetics Laboratory Requisition.
    Please ensure all required information, including patient's clinical history/indication, is provided on the requisition.
     
    Order Restrictions:None
     
    Indications:This screen is a simple, rapid and sensitive method for the initial investigation of disorders resulting in increased excretion of thiol-containing metabolites (i.e., homocystinuria and cystinuria).
    This test should not be used to monitor known homocystinuria or cytinuria patients on treatment as this is a qualitative test.
    Method:Increased urinary homocystine or cystine excretion is detected colorimetrically with the addition of sodium cyanide and sodium nitroprusside. Positive and negative controls are run with patient samples.
    Method Details:A positive nitroprusside test indicating the presence of either increased urine homocystine or cystine will result in reflexively tested amino acid and total homocysteine measurements on this sample, volume permitting.
     
    Reference Interval:N/A
     
    Comments:Contact ACH Biochemical Genetics Laboratory (403-955-7379) for priority turn-around.
     
     
    Last Updated On:Tuesday, May 22, 2018
    Date of Last Review:Jan 2 2018 12:00AM