Lung Cancer

Cancer Care Alberta

Lung cancer is the second most common cancer among adults and the leading cause of cancer-related deaths in both men and women, with over 70% of cases diagnosed at an advanced stage.

In Alberta, 1 in 13 people are expected to develop lung cancer in their lifetime though early detection through screening in high-risk individuals is improving outcomes.


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Quick Reference| Referrals| Risk Factors| Signs & Symptoms|Provider Resources|Patient Resources


Lung Cancer in Never Smokers

Lung cancer in never smokers (LCINS) is:

  • Epidemiological and biologically distinct
  • More common in women than men
  • 5th leading cause of cancer related deaths in adults
  • Part of the 28% of lung cancers in Canada that are not attributed to smoking

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Referrals

Pathways & Referrals


Referrals for Recurrence

Contact the treating oncologist to determine how to refer the patient back to the cancer centre. If the oncologist's contact information is not available, search 'lung cancer' in the Alberta Referral Directory for the most up-to-date information and instructions for referral.

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Risk Factors

  • Second-hand smoke exposure
  • History of COPD
  • Previous cancer
  • History of TB, silicosis
  • Asbestos, radon, wood dust, silica exposure
  • Female
  • East Asian ancestry
  • Smoker, former smoker, second-hand smoke exposure
  • History of COPD
  • Previous cancer
  • History of TB, silicosis
  • Asbestos, radon, wood dust, silica exposure

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Signs & Symptoms

Lung cancer is being increasingly diagnosed in never/nonsmokers. Signs and symptoms of lung cancer are often only present in advanced stage disease (stage 3 & 4).

Presentation of any of the Following

  • Hemoptysis
  • New finger clubbing
  • Suspicious cervical lymphadenopathy
  • Dysphagia
  • Features of metastatic lung cancer
  • Features suggestive of paraneoplastic syndromes

Unexplained Symptoms for > 3 Weeks (or sooner in patients with risk factors)

  • Cough
  • Weight loss/loss of appetite
  • Shortness of breath
  • Chest and/or shoulder pain
  • Abnormal chest signs
  • Hoarseness

Next Steps

  • Order chest x-Ray (PA & LAT) using diagnostic imaging requisition. For triage include: risk factors, relevant history, area of concern
  • Order baseline bloodwork (CBC, extended electrolyte, liver function test)

Presentation of Any of the Following

  • Two or more episodes of hemoptysis (1 tbsp/15ml or more of clotted blood)
  • Supraclavicular lymphadenopathy
  • Incidental CT finding: any solid or ground glass nodule greater than 1cm

Abnormal Chest X-Ray Findings Triggering Suspicion of Cancer

  • Single or multiple pulmonary nodules
  • Mediastinal or hilar lymphadenopathy
  • Unexplainable large unilateral pleural effusion
  • Infiltrate, consolidation or effusion attributed to pneumonia and not resolved in 6-week follow-up X-ray

Next Steps

  • Order CT scan with contrast of thorax, abdomen and pelvis. Using diagnostic imaging requisition. Include: risk factors, relevant history, previous related test results
  • Order baseline blood work (CBC, extended electrolyte, liver function test)
  • Urgent referral to Alberta Thoracic Oncology Program (ATOP)

To be Managed at the Emergency Department

  • Signs of superior vena cava obstruction (swelling of the face or neck with fixed elevation of jugular venous pressure, prominent veins on chest)
  • Stridor
  • Massive hemoptysis (more than 1 cup/250ml in 24 hrs)
  • New neurological signs (suggestive of brain metastases or cord compression)

Next Steps

  • Refer to emergency department
  • Or call RAAPID

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Provider Resources

What's New: Free Webinar Series

Lung Cancer Canada
What's New From

Literature for Lung Cancer in Never Smokers


2023 Lung Cancer for Primary Care

Lung Health Foundation
Free webinar with Dr. Stephanie Snow, medical oncologist, President of Lung Cancer Canada


Creating Safe Connections: Towards Equity-Informed Preventative Care

Free e-learning course from The University of British Columbia helps primary care providers integrate equity-oriented, trauma- and violence-informed care (TVIC) into their practice. Using lung cancer screening and smoking cessation as examples, it teaches how to address barriers to healthcare access. The course supports policy development for TVIC in clinical settings.

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